The Mystery

Most people think dreams are private, just figments of their own subconscious. Flickering images, leftover thoughts, bizarre narratives made up by a brain trying to organize its day. But that's a shallow interpretation of something far more profound. Because sometimes, what you dream wasn't yours to begin with. And sometimes, you're not the only one dreaming it. All over the world, from Indigenous tribes to ancient mystery schools, there have been whispers of what are now called 'shared dreams'. Two people, sometimes strangers, waking up with the same memory of the same place, the same events, the same conversation. They weren't dreaming alone. They were meeting, somewhere beyond the limits of the physical, in what Thoth and others described as the astral commons. A realm where minds untethered from bodies can converge. You might brush it off as coincidence, but science is slowly catching up. Studies in consciousness research including work by pioneers like Dr. ...

Every night as your body sinks into sleep, something extraordinary begins. Your breath slows, your muscles relax, and your mind drifts into what science calls the REM stage. But what they don't fully explain, what they can't explain with electrodes and graphs, is that in this moment, your consciousness slips through the cracks of physical perception and begins to move. Where it goes depends on one thing, vibration. And this is the part they've hidden, not just from textbooks, but from your entire culture. You've been taught to believe that dreams are random firings in a resting brain, leftovers from the day, useless imagery. But ancient knowledge, especially the teachings of Thoth, tells a different story entirely. Dreams are not noise. They're records. They're snapshots of the places your consciousness visits when your physical senses go offline. And when you begin to remember them, not just the content, but the feeling behind them, you realize something earths...

The development of a prolonged N,N-Dimethyltryptamine (DMT) experience would be an important step towards allowing for a closer study of its phenomenology and neurobiological effects, and would make it possible to control the length, intensity, and dynamics of the DMT experience, with the potential for real-time adjustment. This could make extended DMT a valuable tool in conjunction with therapy, to tailor the psychedelic effects to the individual needs of each patient and their clinical condition, as well as for consciousness research, whereby the intensity of the DMT experience can be adjusted according to specific hypotheses and research questions. Continuous infusions of DMT were safely administered for up to 90 min and the infusion rates were reported to be determined via a previous pilot study with six subjects. However, this report lacked information on how strong and sustained these effects were over time. Another approach was proposed, aiming to generate stable subjective effe...

When ingested orally, N,N-Dimethyltryptamine (DMT) is rapidly metabolized in the gastrointestinal system by monoamine oxidase (MAO) which renders it psychologically inactive. In both recreational and ritual settings, DMT is commonly given in the form of ayahuasca, a brew containing DMT and harmala alkaloids that inhibit MAO, which upon oral ingestion, leads to alterations in consciousness lasting for 4–6 h. Alternatively, DMT can be inhaled (vaping/smoking), or administered parenterally (e.g., intramuscularly, or intravenously as a bolus). These forms of administration result in a very short duration of subjective effects: when administered via bolus intravenous (IV) injection, DMT’s subjective effects begin within seconds, reaching their peak intensity within 2–3 min and subsiding thereafter, with negligible effects felt after about 30 min. IV DMT administration allows for precise control over dosing, which makes it the preferred route of administration for investigating its effects i...

N,N-Dimethyltryptamine (DMT) is a naturally occurring psychedelic with a mechanism of action linked to agonism at the 5-HT2A receptor. It can induce a transient and immersive altered state of consciousness, characterized by complex and vivid visual imagery, as well as somatosensory, affective and cognitive effects. Perhaps most distinctive to the experience is the frequently reported sense of immersion into what is perceived to be another world or dimension. This experience is twinned with reports of encountering ‘entities’ or ‘sentient presences’ in about half of cases. The DMT experience shares similarities with the near-death experience and is frequently deemed profound, at times leading to lasting revisions of beliefs about the nature of reality and consciousness. DMT is therefore a powerful tool for the study of consciousness. The subjective experience of immersion into a richly content-full experience, while feeling decoupled from the immediate environmental sensorium, makes DMT ...